Dataset Information


Genomic Analysis Reveals Pleiotropic Alleles at EDN3 and BMP7 Involved in Chicken Comb Color and Egg Production

ABSTRACT: Dongxiang blue-shelled chicken, an indigenous chicken breed in China, has segregated significantly for the dermal hyperpigmentation phenotype. Two lines of the chicken have been divergently selected with respect to comb color for over 20 generations. The recent selection has also resulted in a significant difference in egg production. The red comb line (RCL) chicken produces significantly higher number of eggs than that by the dark comb line (DCL) chicken. The objective of this study was to explore potential mechanisms involved in the relationship between comb color and egg production among chickens. We performed genome-wide association study to identify candidate genes associated with chicken comb color using SNP array data, and we conducted selective sweep analysis to identify putative regions of selection harboring pleiotropic genes affecting both comb color and egg production. Overall design: Affymetrix Axiom 600 K Chicken Genotyping Array were performed according to the manufacturer's directions on DNA extracted from brachial veins of chickens. A total of 178 female chickens were used in the study.

INSTRUMENT(S): [Axiom_GW_GT_Chicken] 600K Affymetrix Axiom® HD Genotyping Array

ORGANISM(S): Gallus gallus  

SUBMITTER: Xuemei Deng  

PROVIDER: GSE124906 | GEO | 2019-06-04


Dataset's files

Action DRS
GSE124906_Matrix_table_for_SNP_calls.txt.gz Txt
GSE124906_RAW.tar Raw
filelist.txt Txt
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