Novel mutations segregating with Complete Androgen Insensitivity Syndrome and their molecular characteristics.

ABSTRACT: We analysed three interesting, rare cases of CAIS (Complete Androgen Insensitivity Syndrome) and report three hitherto undisclosed causes of the disease. Comparative RNA-Seq analysis of CAIS and control samples (3 testicular oligobiopsies from men with normal spermatogenesis) revealed 4,293 significantly deregulated genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE125222 | GEO | 2019/02/18

REPOSITORIES: GEO