Paradoxical CD4 decline on ART: a novel, rare and perplexing immunologic outcome

ABSTRACT: The goal of antiretroviral therapy (ART) is to suppress HIV-1-replication and reconstitute CD4-T-cells. Here, we report on HIV-infected individuals, who had a paradoxical decline in CD4-T-cells despite ART-mediated suppression of plasma HIV-1 load (plHIV-1). We defined such immunological outcome as extreme immune decline (EXID).

ORGANISM(S): Homo sapiens

PROVIDER: GSE125223 | GEO | 2020/01/31

REPOSITORIES: GEO