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Global gene expression profile of wild type and Smad4-deficient Th17 cells cultured at 37°C and 39.5°C

ABSTRACT: Febrile temperature enhanced Th17 differentiation in Smad4 SUMOylation-dependent manner. Smad4-deficiency impaired the febrile temperature-enhanced Th17 differentiation. In order to understand how febrile temperature and Smad4 contribute to Th17 pathogenicity, we conducted transcriptional analysis of wild type and Smad4-deficient Th17 cells cultured at 37°C and 39.5°C (Day 3).

ORGANISM(S): Mus musculus

PROVIDER: GSE125264 | GEO | 2020/03/01

REPOSITORIES: GEO

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