Gene expression data from UMUC-14 following FGFR3 knock-down using FGFR3 siRNAs

ABSTRACT: To better understand the molecular mechanisms underlying altered-FGFR3 oncogenic activity in bladder carcinomas, we made use of UMUC-14 cell lines, which endogenously expressed a mutated activated form of FGFR3 (FGFR3-S249C), the growth and transformation of these cell lines being dependent on activated-FGFR3 activity. We conducted a gene expression analysis using Affymetrix DNA arrays in this cell line treated or not with FGFR3 siRNAs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE125547 | GEO | 2020/12/31

REPOSITORIES: GEO