Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

All the regulated lncRNAs in breast cancer tissues compared to adjacent normal breast tissues

ABSTRACT: Circulating transcriptional landscapes between breast cancer tissues and adjacent normal tissues were compared using the Affymetrix Human OE LncRNA Microarray with probes for profiling of 63542 human lncRNAs. Goal was to investigate potential lncRNAs involved in breast cancer progression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE125677 | GEO | 2019/01/26

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

All the regulated lncRNAs in breast cancer tissues compared to adjacent normal breast tissues

Project description:All the regulated lncRNAs in breast cancer tissues compared to adjacent normal breast tissues

| PRJNA517149 | ENA

All the regulated lncRNAs in breast cancer stem cells (BCSCs, CD44+CD24- sorted)MCF-7 cells compared to non-BCSCs (non-CD44+CD24- sorted) MCF-7 cells

Project description:Circulating transcriptional landscapes between BCSCs and non-BCSCs were compared using the Affymetrix Human OE LncRNA Microarray with probes for profiling of 63542 human lncRNAs. Goal was to investigate potential lncRNAs involved in BCSCs progression.

2019-01-26 | GSE125678 | GEO

Expression data from breast cancer tissues and adjacent normal tissues

Project description:Expression data from breast cancer tissues and adjacent normal tissues

| PRJNA429856 | ENA

All the regulated lncRNAs and mRNAs in BCSCs derived exosomes compared to non-BCSCs derived exosomes

Project description:Transcriptional landscapes between exosomes derived from BCSCs and non-BCSCs were compared using the LC Human ceRNA array V1.0 (4*180K, Design ID:085202) Microarray. Goal was to investigate potential lncRNAs involved in breast cancer progression through enveloping into exosomes.

2024-01-31 | GSE254074 | GEO

Upregulated mRNAs and lncRNAs in chemoresistant breast cancer

Project description:Chemoresistance is a major cause of poor prognosis of breast cancer.More and more mRNAs and lncRNAs are reported to upregulate chemoresistance in breast cancer.To explore the how mRNAs and lncRNAs involved in chemoresistance of breast cancer,we sceened upregulated mRNAs and lncRNA from parental MCF-7 , chemoresistant MCF-7 cells as well as 4 breast cancer tissue sensitive to chemotherapy and 4 resistant to chemotherapy . Total RNA was extracted using Trizol reagent. Agilent Human lncRNA Microarray V6 (4*180K) was used to analyze the global profiling of human lncRNAs and protein-coding transcripts in these samples. The microarray contains 83,835 lncRNAs and 27,233 coding genes.

2020-02-25 | E-MTAB-8787 | biostudies-arrayexpress

miRNA expession data in breast cancer and adjacent normal tissues

Project description:We select 3 pairs of tissue samples, including 3 breast tissues and 3 adjacent tissues, and then perform miRNA chip detection to find differential miRNAs. We used microarrays to identify differential expressed miRNAs in breast cancer and paired normal breast tissue

2020-01-16 | GSE143564 | GEO

lncRNAs and mRNAs expression data in esophageal squamous cell carcinoma(ESCC) and adjacent normal tissues

Project description:The differential expression profile of lncRNAs and mRNAs in esophageal squamous cell carcinoma in high-incidence areas of China was constructed and co-expression correlation analysis was performed. The expression profile of lncRNAs in ESCC tissues was significantly different from that in adjacent normal tissues. Co-expression analysis revealed that lncRNA may be involved in the occurrence and development of esophageal cancer, thus providing a new basis for the diagnosis and treatment of esophageal cancer.

2023-09-10 | GSE157804 | GEO

circRNA expression in breast cancer and adjacent non-tumor breast tissues

Project description:circRNA expression in breast cancer and adjacent non-tumor breast tissues

| PRJNA756311 | ENA

Expression data from breast cancer tissues and adjacent normal tissues

Project description:The early-onset breast cancer patients (age ≤40) often display higher incidence of axillary lymph node metastasis, and poorer five-year survival than the late-onset patients. To identify the genes and molecules associated with poor prognosis of early-onset breast cancer, we examined gene expression profiles from paired breast normal/ tumor tissues, and coupled with Gene Ontology and public data base analysis. Our data showed that the expression of GAS7b gene was lower in the early-onset breast cancer patients as compared to the elder patients. We found that GAS7 was associated with CYFIP1 and WAVE2 complex to suppress breast cancer metastasis via blocking CYFIP1 and Rac1 protein interaction, actin polymerization, and β1-integrin/FAK/Src signaling. We further demonstrated that p53 directly regulated GAS7 gene expression, which was inversely correlated with p53 mutations in breast cancer specimens. Our study uncover a novel regulatory mechanism of p53 in early-onset breast cancer progression through GAS7-CYFIP1 mediated signaling pathways.

2018-01-13 | GSE109169 | GEO

Genome-wide microarray analysis to identify the differentially expressed patterns of lncRNAs of cholesteatoma tissues compared with matched normal skin tissues.

Project description:We performed genome-wide microarray analysis to identify the differentially expressed patterns of lncRNAs in cholesteatoma. Our data indicated that lncRNA expression profiles were significantly altered in cholesteatoma compared with normal skin tissues. A total of 787 lncRNAs were identified (fold change ≥2.0, P < 0.05), consisting of 181 upregulated and 606 downregulated lncRNAs.

2018-05-09 | GSE102673 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data