P53-inducible long non-coding RNAs encode functional peptides in hepatocellular carcinoma cells [RNA-seq]

ABSTRACT: To identify p53-regulated lncRNAs responsive to DNA damage in human hepatocellular carcinoma (HCC) cells, we conducted paired-end and strand-specific RNA-seq using HepG2 wild-type and p53-knockout (HepG2-KO-p53) cells, which were devoid of p53 protein, using the CRISPR-Cas9 system treated with or without the DNA-damaging agent adriamycin (ADR)

ORGANISM(S): Homo sapiens

PROVIDER: GSE125756 | GEO | 2020/07/18

REPOSITORIES: GEO