Mapping polymerase usage by tracking ribonucleotide incorporation (HydEn-seq) during DNA replication

ABSTRACT: We devised and improved on our hydrolytic end sequencing (HydEn-seq) that mapping ribonucleotide incorporation in genome and used this method to track DNA replicative polymerase usage. We uncovered striking exceptions to canonical polymerase division of labor in Saccharomyces cerevisiae and Schizosaccharomyces pombe.

ORGANISM(S): Saccharomyces cerevisiae Schizosaccharomyces pombe

PROVIDER: GSE125855 | GEO | 2019/01/30

REPOSITORIES: GEO