Transcriptional profile of LPS-stimulated murine macrophages treated with bacterially derived fatty acid

ABSTRACT: We used RNA-seq to profile the effect of a bacterially derived fatty on LPS-stimulated murine macrophages. From the transcriptional response, there was a significant decrease of inflammatory signals with lipid treatment, and pathway analysis of differentially expressed genes suggests PPAR alpha as potential anti-inflammatory mechanism.

ORGANISM(S): Mus musculus

PROVIDER: GSE125930 | GEO | 2019/02/01

REPOSITORIES: GEO