Single-cell analysis of cardiogenesis reveals basis for organ level developmental defects

ABSTRACT: We employed single-cell RNA sequencing to interrogate early cardiac progenitor cells as they become specified during normal and Hand2-deficient cardiogenesis, to understand how dysregulation of specific cellular sub-populations can have catastrophic consequences.

ORGANISM(S): Mus musculus

PROVIDER: GSE126128 | GEO | 2019/05/27

REPOSITORIES: GEO