Project description:the gene expression profiling results provide important information for the genes regulated by crosstalk between Shp2 and Pten mediated signal pathways Total RNA was extracted from CD71mid Ter119high erythroblasts isolated from the bone marrow of wide type, Shp2 knock-out, Pten knock-out and double knock-out mice
Project description:We employed whole genome microarray expression profiling as a discovery platform to identify gene expression changes after DHTKD1 knock-out RNAs of spinal cords of 8-weeks-old wild-type (n=3) and DHTKD1 knock-out mice (n=3) were used to identify gene expression.
Project description:A Knock out of the snf1 kinase homolog of Leishmania major was developed by CRISPR approach.Toidentify the change in protein expression a whole peoteome analysis was done to identify changes in gene expression levels at whole proteome level.
