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Gene expression analysis of a subcutaneous MV4;11 tumor treated with curaxin CBL0137.

ABSTRACT: The aim of this experiment was to identify how CBL0137 decreased tumor growth in a subcutaneous MV4;11 xenograft model by investigating the gene expression changes induced upon treatment.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE126442 | GEO | 2019/02/13

REPOSITORIES: GEO

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Gene expression analysis of a subcutaneous MV4;11 tumor treated with curaxin CBL0137.

Project description:Gene expression analysis of a subcutaneous MV4;11 tumor treated with curaxin CBL0137.

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Project description:We analyzed changes in abundance of RNAs in mouse embryonic fibroblasts (MEF) from wild type and p53 knockout mice and in lungs of NIH Swiss mice upon treatment with 1microM (cells) or 60mg/kg IV (mice) of curaxin CBL0137 for 24 hours. CBL0137 is chromatin destabilizing agent.

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