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Effect of Omomyc treatment on human lung adenocarcinoma cell lines

ABSTRACT: Analysis of H1975, A549 and H1299 cells treated with 12.8 µM Omomyc or vehicle (PBS) for three days.

ORGANISM(S): Homo sapiens

PROVIDER: GSE126453 | GEO | 2019/04/01

REPOSITORIES: GEO

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Effect of Omomyc treatment on human TNBC MDAMB231 cell line

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Whole transcriptome analysis of T11 treated with FPP-1746-Omomyc

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Effect of Omomyc in vivo treatment on lung adenocarcinoma of KRasLSL-G12D/+ transgenic mouse

Project description:Analysis of Kras-driven lung adenocarcinoma of mice intranasally treated with 2.37 mg/kg Omomyc or vehicle (10 mM sodium acetate pH 6.5) for three days. KRasLSL-G12D/+ mice were treated with Omomyc by intranasal administration sixteen weeks after Adeno-Cre infection. Mice (n=2 for vehicle treated and n=3 for Omomyc treated group) were euthanized three days post-treatment and lung tumors were excised and frozen at -80ºC until processing.

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Concomitant targeting of viral and host methyltransferases is essential for attenuating SARS-CoV-2

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Transcriptional response to serum stimulation of Rat1 fibroblasts in the presence or absence of the Myc interfering molecule termed Omomyc.

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