Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

NanoString analysis of immune genes in the tumor at day 10 after injection into WT and Rnf5-/- mice

ABSTRACT: The NanoString analysis of 770 genes expressed by 24 immune cell types in the tumors at 10 days after injection were performed. The Nanostring analysis uncovered marked difference in key immune regulatory networks associated with T, DC, NC and macrophage function

ORGANISM(S): Mus musculus

PROVIDER: GSE127753 | GEO | 2019/03/04

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Siah2 control of T-regulatory cells limits anti-tumor immunity

Project description:The NanoString analysis of 784 genes expressed by 24 immune cell types in the melanoma cell at 11 days after injection were performed. The Nanostring analysis uncovered marked difference in key immune regulatory networks associated with T, DC, NC and macrophage function

2019-07-17 | GSE134328 | GEO

NanoString analysis of immune genes in the tumor at day 10 after injection into WT and Rnf5-/- mice

Project description:NanoString analysis of immune genes in the tumor at day 10 after injection into WT and Rnf5-/- mice

| PRJNA525280 | ENA

NanoString PanCancer Immune Profiling of 4′‐bromo‐resveratrol treated BrafV600E/PtenNULL melanoma mice

Project description:We performed differential gene expression analysis using high throughput multiplex analysis via NanoString nCounter PanCancer Immune Profiling panel, which analyzes 770 genes related to cancer-immune pathways (cancer progression, chemokines and cytokines and their receptors, and innate and adaptive immune response). nSolver software was used to analyze the data and a heat map was generated to show differential expression of 770 genes. Further, using a fold cut-off of ≥2 and p-value <0.05, we observed that 4'-BR significantly modulated expression of multiple cancer immune genes.

2021-11-29 | GSE168564 | GEO

Nanostring

Project description:Nanostring PanCancer immune profiling data for The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancer

| EGAD00010001515 | EGA

ASS lime injection - injection site

Project description:ASS lime injection - injection site

| PRJEB6137 | ENA

Genome-wide expression study of the responses of murine NK cells and dendritic cell subsets after poly(I:C) injection

Project description:The injection of the pathogen-associated molecular pattern Polyinosinic-polycytidylic acid (poly(I:C)) leads to the activation of various immune cells, including dendritic cells (DCs) and Natural Killer (NK) cells. This activation is due to different innate cytokines produced early after injection, in particular IFN-I. The objective of the study was to compare the pattern of expression of IFN-I stimulated genes between DC and NK cells. The project focused on a specific subset of conventional DC, CD8a DC, which responsiveness to IFN-I determines the capacity to activate CD8 T cells by cross-presentation of exogenous antigens. To identify the responses to IFN-I selectively induced in CD8a+ DC, we compared their gene expression profile to that of NK cells, using gene chips, before and after poly(I:C) stimulation. This study includes data from CD8a+ cDCs and NK cells purified by flow cytometry from the spleen of WT C57BL/6 mice, under steady-state conditions or 3 hours after administration of 100 ug poly(I:C) by intravenous injection. Two independent replicates were made for each cell type.

2012-10-17 | E-GEOD-39556 | biostudies-arrayexpress

Mammary Tumor-Derived Transplants as Breast Cancer Models to Evaluate Tumor-Immune Interactions and Therapeutic Responses

Project description:To investigate mTDT transcriptional features using the Nanostring pancancer io 360 gene expression panel that consists of 770 unique genes involved in the interplay between the tumor, microenvironment and immune response.

2021-12-01 | GSE152403 | GEO

Genome-wide expression study of the responses of murine NK cells and dendritic cell subsets after poly(I:C) injection

2012-10-17 | GSE39556 | GEO

Gene-expression analysis after intratumoral treatment with CMV-derived peptides

Project description:Analysis of whole tumor mRNA with nanostring PanCancer Immune profiling platforrm In the study presented, we analyzed the expression of 770 genes from the total tumor RNA extracted from 24 solid murine tumors

2022-07-06 | GSE205574 | GEO

ASS lime injection - injection site metagenomic assembly

Project description:EMG produced TPA metagenomics assembly of the ASS lime injection - injection site (ASS lime injection - injection site) data set

| PRJEB22628 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data