Gene expression profile during senescence induced by LSG1 knockdown

ABSTRACT: In the present study, we analyze the effect of knocking down LSG1 and KRas(V12D) overexpression in MRC5 cells in the transcriptome using Ampliseq RNA sequencig. We observed that shLSG1 induced a potent senescence response that is characterized by the activation of ER-Stress and cholesterol biosynthetic pathway

ORGANISM(S): Homo sapiens

PROVIDER: GSE128055 | GEO | 2019/06/11

REPOSITORIES: GEO