Genomics

Dataset Information

0

Ribosome profiling of HSV-1 infected cells


ABSTRACT: Primary human foreskin fibroblasts (HFF) were infected with wild-type simplex virus 1 (HSV-1) strain 17 at a multiplicity of infection (MOI) of 10. Ribosome profiling was performed at various times during infection with minor modification to the protocol described in Stern-Ginossar N et al., Science 2012. Translation start site profiling was performed by culturing cells in presence of Harringtonin or Lactimidomycin for 30 min prior to cell harvest. Overall design: Ribosome profiling was performed a 0, 1, 2, 4, 6 and 8 h post infection. Translation start site profiling was performed using Harringtonin (2µ/ml for for 30 min) or Lactimidomycin (50µM for 30 min) prior to cell lysis. Two biological replicates were analysed.

INSTRUMENT(S): Illumina HiSeq 2000 (Homo sapiens)

SUBMITTER: Florian Erhard  

PROVIDER: GSE128322 | GEO | 2020-04-07

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
GSE128322_HSV.A.tsv.gz Tabular
GSE128322_HSV.B.tsv.gz Tabular
GSE128322_Human.A.tsv.gz Tabular
GSE128322_Human.B.tsv.gz Tabular
Items per page:
1 - 4 of 4

Similar Datasets

2019-01-01 | S-EPMC6361465 | BioStudies
2020-07-04 | E-MTAB-8045 | BioStudies
2012-01-01 | S-EPMC3443142 | BioStudies
2021-01-01 | S-EPMC7797918 | BioStudies
2014-12-01 | GSE58207 | GEO
2015-10-23 | E-GEOD-74279 | ArrayExpress
2016-01-01 | S-EPMC4909307 | BioStudies
2018-01-01 | S-EPMC5916843 | BioStudies
2018-01-01 | S-EPMC5778647 | BioStudies
2016-01-01 | S-EPMC5074520 | BioStudies