Genomics

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A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling]

ABSTRACT: Human iPS cells with different mutations linked to Alzheimer's Disease were differentiated into neurons and subjected to ribosome profiling to identify Alzheimer's Disease associated changes

ORGANISM(S): Homo sapiens

PROVIDER: GSE128344 | GEO | 2019/08/08

REPOSITORIES: GEO

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