Ontology highlight
ABSTRACT:
INSTRUMENT(S): Mouse Skeletal Muscle Array
SUBMITTER: Christoph Däpp
PROVIDER: GSE1284 | GEO | 2004-09-30
SECONDARY ACCESSION(S): PRJNA89915
REPOSITORIES: GEO
Physiological genomics 20041012 1
This study investigated the use of the hindlimb suspension (HS) and reloading model of mice for the mapping of ultrastructural and gene expressional alterations underlying load-dependent muscular adaptations. Mice were hindlimb suspended for 7 days or kept as controls (n = 12). Soleus muscles were harvested after HS (HS7, n = 23) or after resuming ambulatory cage activity (reloading) for either 1 day (R1, n = 13) or 7 days (R7, n = 9). Using electron microscopy, a reduction in mean fiber area (- ...[more]