Genomics

Dataset Information

30

Control


ABSTRACT: Control mice, 14 days Keywords: repeat sample

INSTRUMENT(S): Mouse Skeletal Muscle Array

SUBMITTER: Christoph Däpp  

PROVIDER: GSE1284 | GEO | 2004-09-30

SECONDARY ACCESSION(S): PRJNA89915

REPOSITORIES: GEO

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Publications

Transcriptional reprogramming and ultrastructure during atrophy and recovery of mouse soleus muscle.

Däpp Christoph C   Schmutz Silvia S   Hoppeler Hans H   Flück Martin M  

Physiological genomics 20041012 1


This study investigated the use of the hindlimb suspension (HS) and reloading model of mice for the mapping of ultrastructural and gene expressional alterations underlying load-dependent muscular adaptations. Mice were hindlimb suspended for 7 days or kept as controls (n = 12). Soleus muscles were harvested after HS (HS7, n = 23) or after resuming ambulatory cage activity (reloading) for either 1 day (R1, n = 13) or 7 days (R7, n = 9). Using electron microscopy, a reduction in mean fiber area (-  ...[more]

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