Plpp1 protects MaSC (mammary stem cell) from malignant proliferation
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ABSTRACT: Mammary stem cell enriched subpopulations P4 (CD24+CD29hi) and luminal progenitor subpopulation P5 (CD24+CD29lo) were sorted from mammary gland from adult wild type C57BL6 mice and Plpp1 KO mice. The trascriptome profiles are determined and compared. In addition, P4 and P5 cells were sorted from ex vivo cultured mammary gland tissues with and without LPA treatment, the effects of LPA stimulation is investigated.
ORGANISM(S): Mus musculus
PROVIDER: GSE128467 | GEO | 2025/12/20
REPOSITORIES: GEO
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