Gene Expression Analysis of RBM5 KO in Brain

ABSTRACT: This study analyzed the effect of RBM5 gene deletion in cortical brain tissue on differential gene expression/splicing changes 48h after a traumatic brain injury (TBI). TBI was induced in WT vs. KO mice by controlled cortical impact (CCI) injury. The four grouops included: (1) Sham-WT, (2) CCI-WT, (3) Sham-KO, and (4) CCI-KO. The objective of this study was to test if RBM5 KO decreased the expression of cell death mediators in the contused brain 48h post-injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE128543 | GEO | 2021/05/12

REPOSITORIES: GEO