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Genome-wide identification of AP-2α by ChIP-chip in breast cancer cell line MCF7

ABSTRACT: The AP-2 family of transcription factors is involved in the regulation of embryonic development, cell proliferation and tumorigenesis. To date, five members of the AP-2 family have been identified: AP-2α, AP-2β, AP-2γ, AP-2δ and AP-2ε. All AP-2 proteins bind as homo- or heterodimers to the consensus sequence of 5'- GCCNNNGGC-3' and directly regulate transcription of their target genes. Among these, AP-2α is the best-characterized gene.

ORGANISM(S): Homo sapiens

PROVIDER: GSE128589 | GEO | 2020/12/08

REPOSITORIES: GEO

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