Mapping global miR-29a targets in pancreatic cancer adenocarcinoma (PDAC) cells using Next Generation Sequencing approach
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ABSTRACT:
ORGANISM(S): Homo sapiens
PROVIDER: GSE128663 | GEO | 2022/03/20
REPOSITORIES: GEO
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Project description:In this study, we aim to understand the role of miR-29a in in regulating hPSCs. Identification of the differentially expressed direct and indirect miR-29a targets and the associated pathways from the RNASeq data delineates gene interactions and networks essential for activated PSCs in pancreatic ductal adenocarcinoma (PDAC) in regulating desmoplasia and tumor-stomal crosstalk, which are crucial mechanisms for PDAC progression.
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Project description:Mapping global miR-29a targets in pancreatic cancer adenocarcinoma (PDAC) cells using Next Generation Sequencing approach
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