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MicroRNA-204-5p is a tumor suppressor and potential therapeutic target in head and neck squamous cell carcinoma.

ABSTRACT: To understand molecular mechanisms underlying miR-204-5p mediated suppression of HNSCC progression, we performed RNA-seq analysis in UM-SCC1 cells transfected with miR-204-5p mimics and control mimics. The expression of JAK2, SNAI2, TGFBR2, MAP2K4, involved in both EMT and STAT3 signaling, were all decreased in cells treated with miR-204-5p mimics.

ORGANISM(S): Homo sapiens

PROVIDER: GSE128773 | GEO | 2020/01/21

REPOSITORIES: GEO

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MiR-204-5p may Regulate Oxidative Stress in Myopia and Myopia-Related Retinopathy

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