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Gene expression analysis on the immortalized human mesothelial cell lines with different morphologies.

ABSTRACT: Establishment of immortalized human omental mesothelial cell lines (HOMCs) resulted in cloning three sublines (HOMC-B1, A4 and D4) with different morphologies. HOMC-B1 forms an epithelial-like monolayer. HOMC-A4 shows spindle-shaped morphology (storiform pattern). HOMC-D4 displayed an intermediate appearance. With the aim of exploring the key genes on decision of cellular morphology, gene expression of HOMC cell lines were analyzed along with conventional normal pleura-derived cell line, MeT-5A.

ORGANISM(S): Homo sapiens

PROVIDER: GSE128788 | GEO | 2021/03/31

REPOSITORIES: GEO

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