Genomics

Dataset Information

0

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple mutated AML

ABSTRACT: HLF was knocked down in a primary human triple mutated AML sample using shRNA against human HLF versus shRNA against luciferase (shLuc) as control to determine gene expression changes 72 hours after lentiviral transduction.

ORGANISM(S): Homo sapiens

PROVIDER: GSE128848 | GEO | 2022/03/26

REPOSITORIES: GEO

Json Xml

Similar Datasets

Unknown Mutation analysis of JAK2V617F, FLT3-ITD, NPM1, and DNMT3A in Chinese patients with myeloproliferative neoplasms.
| S-EPMC4034537 | biostudies-literature
Transcriptomics Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple mutated AML
2022-03-28 | GSE129094 | GEO
Unknown Outcomes of Older Patients with NPM1 Mutated and FLT3-ITD Negative Acute Myeloid Leukemia Receiving Allogeneic Transplantation.
| S-EPMC7000468 | biostudies-literature
Unknown Fludarabine, High-Dose Cytarabine and Idarubicin-Based Induction May Overcome the Negative Prognostic Impact of FLT3-ITD in NPM1 Mutated AML, Irrespectively of FLT3-ITD Allelic Burden.
| S-EPMC7796342 | biostudies-literature
Unknown DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
| S-EPMC4908977 | biostudies-literature
Unknown Arsenic trioxide induces autophagic degradation of the FLT3-ITD mutated protein in FLT3-ITD acute myeloid leukemia cells.
| S-EPMC7150460 | biostudies-literature
Unknown Maintenance therapy for <i>FLT3-ITD</i>-mutated acute myeloid leukemia.
| S-EPMC7927878 | biostudies-literature
Unknown <i>NPM1</i> and <i>FLT3-ITD/TKD</i> Gene Mutations in Acute Myeloid Leukemia.
| S-EPMC7885130 | biostudies-literature
Unknown Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia.
| S-EPMC4544001 | biostudies-literature
Unknown Allogeneic transplant for FLT3-ITD mutated AML: a focus on FLT3 inhibitors before, during, and after transplant.
| S-EPMC6826920 | biostudies-literature