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Inter-myeloid cell synaptic antigen dispersal drives diversified anti-tumor T cell priming

ABSTRACT: Using a labelled tumor antigen we identify dendritic cell subsets containing tumor derived antigen in the tumor draining lymph nodes and used these to stimulate anti-tumor OTI CD8 T cells. These were subsequently interrogated by RNAseq to determine how diverse DC subsets drive distinct patterns of CD8 T cell differentiation

ORGANISM(S): Mus musculus

PROVIDER: GSE128980 | GEO | 2020/11/27

REPOSITORIES: GEO

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Inter-myeloid cell synaptic antigen dispersal drives diversified anti-tumor T cell priming

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