Aging-exacerbated demyelinating injury is associated with microglia-derived reactive oxygen species: alleviation by indapamide

ABSTRACT: We sequenced the transcriptome of young (6-8 week) and middle-aged (8-10 month old) C57BL/6 female mice that were naïve or had injured ventrolateral spinal cord white matter. We found several differentially expressed genes, many suggesting an altered immune response to injury with advancing age.

ORGANISM(S): Mus musculus

PROVIDER: GSE129000 | GEO | 2019/03/29

REPOSITORIES: GEO