Next Generation Sequencing identifies lymph node lymphatic endothelial cell genes regulated by RANKL

ABSTRACT: Purpose: The objective was to identify genes regulted by RANK signalling in lymph node lymphatic endothelial cells Method: Lymphatic endothelial cells were FACS sorted from peripheral lymph nodes of mice deficient for stromal RANKL (Ccl19 Cre Rankl flox/flox) versus littermate controls (Rankl flox/flox) and processed for bulk RNA sequencing Results: Upregulated and downregulated genes were identified

ORGANISM(S): Mus musculus

PROVIDER: GSE129315 | GEO | 2019/06/01

REPOSITORIES: GEO