Gene expression of zebrafish larvae upon treating with lalistat or U18666A

ABSTRACT: To test if HIF pathway is regulated by lipids in zebrafish larvae, we have employed whole genome microarray expression profiling as a discovery platform to identify induced genes upon lalistat or U18666A treatment. Lalistat is a specific inhibitor for lysosomal acid lipase (LAL), which is required for break down triglyceride or cholesterol ester to release free fatty acids. U18666A is a specific inhibitor for NPC, which is required for export free cholesterol oout of lysosomes.

ORGANISM(S): Danio rerio

PROVIDER: GSE129434 | GEO | 2019/04/07

REPOSITORIES: GEO