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Chromatin structure profiling of mouse muscle stem cells by ATAC-seq

ABSTRACT: By comparing ATAC-seq from freshly isolated satellite cells (QSC), satellite cells isolated 2.5 days post-injury (ASC), and satellite cells cultured for differentiation, we observed a gradual opening of satellite cell chromatin structure during activation and differentiation process. We used ATAC-seq to study the functional role of LncMyod during satellite cell differentiation and identified genes that exhibited decrease of accessibilities to their transcription start sites (TSS). The majority of the regions are myogenesis-related genes, suggesting LncMyod plays a critical role in establishing permissive chromatin environment for myogenic progression.

ORGANISM(S): Mus musculus

PROVIDER: GSE129745 | GEO | 2020/12/08

REPOSITORIES: GEO

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Transcriptome sequencing analysis of LncMyod-knockdown satellite cells by RNA-seq

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2020-12-08 | GSE129766 | GEO

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A Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-mediated mRNA Translation

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2015-08-11 | E-GEOD-68842 | biostudies-arrayexpress

A Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-mediated mRNA Translation

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Histone modifications in LncMyoD-KD mouse muscle stem cells by ChIP-seq

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Expression data from differentiating primary culture of equine satellite cells (ESC) incubated with gamma-oryzanol (GO)

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2018-01-27 | GSE73778 | GEO

Muscle stems cell LC-MS - Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function

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Expression data from differentiating primary culture of equine satellite cells (ESC) incubated with gamma-oryzanol (GO)

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