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Comparative transcriptomic analysis of BA- or BL- associated murine colonic epithelium

ABSTRACT: A huge number of microorganisms are colonized in human gut and the balance of their composition is closely related to human health. Recently, many probiotics such as bifidobacteria or lactobacilli have been introduced in our life as effective agents. However, we have not well understood their beneficial mechanisms including host-bacterial crosstalk To analyze the differences of gene expression between BA- or BL-associated murine colonic epithelium, we performed comparative transcriptomic analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE12997 | GEO | 2011/01/27

SECONDARY ACCESSION(S): PRJNA114251

REPOSITORIES: GEO

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Comparative transcriptomic analysis of BA- or BL- associated murine colonic epithelium

Project description:A huge number of microorganisms are colonized in human gut and the balance of their composition is closely related to human health. Recently, many probiotics such as bifidobacteria or lactobacilli have been introduced in our life as effective agents. However, we have not well understood their beneficial mechanisms including host-bacterial crosstalk To analyze the differences of gene expression between BA- or BL-associated murine colonic epithelium, we performed comparative transcriptomic analysis. Bifidobacterium adolescentis (BA)-associated mice and Bifidobacterium longum (BL)-associated mice were used. Colonic epithelium was isolated and gene expression profile was analyzed. Each 3 samples were analyzed.

2011-01-27 | E-GEOD-12997 | biostudies-arrayexpress

Comparative transcriptomic analysis of BA- or BL- associated murine colonic epithelium after O157 infection

Project description:A huge number of microorganisms are colonized in human gut and the balance of their composition is closely related to human health. Recently, many probiotics such as bifidobacteria or lactobacilli have been introduced in our life as effective agents. However, we have not well understood their beneficial mechanisms including host-bacterial crosstalk. Accordingly, we took advantage of the protective mechanisms of probiotics against lethal infection of enterohemorrhagic Escherichia coli O157:H7 in murine gnotobiote model system

2011-01-27 | GSE12998 | GEO

Comparative transcriptomic analysis of BA- or BL- associated murine colonic epithelium after O157 infection

Project description:A huge number of microorganisms are colonized in human gut and the balance of their composition is closely related to human health. Recently, many probiotics such as bifidobacteria or lactobacilli have been introduced in our life as effective agents. However, we have not well understood their beneficial mechanisms including host-bacterial crosstalk. Accordingly, we took advantage of the protective mechanisms of probiotics against lethal infection of enterohemorrhagic Escherichia coli O157:H7 in murine gnotobiote model system Germ free (GF) mice was used as control. E means O157-monoassociated mice. BAE means B. adolescentis and O157-associated mice. BLE means B. longum and O157-associated mice. Numbers indicate the days after O157 infection.

2011-01-27 | E-GEOD-12998 | biostudies-arrayexpress

Comparative transcriptomic analysis of BA- or BL-

Project description:This SuperSeries is composed of the following subset Series: GSE12997: Comparative transcriptomic analysis of BA- or BL- associated murine colonic epithelium GSE12998: Comparative transcriptomic analysis of BA- or BL- associated murine colonic epithelium after O157 infection Refer to individual Series

2011-01-27 | E-GEOD-13061 | biostudies-arrayexpress

RNA seq analysis of BL/6C57 or BL/6NZB mice

Project description:RNA seq analysis was done on the liver samples of BL/6C57 or BL/6NZB male and female mice at 50 weeks

2021-12-15 | GSE190767 | GEO

Fusobacterium necrophorum BL strain:BL

Project description:Fusobacterium necrophorum BL strain:BL Genome sequencing and assembly

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Murine Ba/F3 Cells: Ba/F3 cells expressing wild type JAK2 (WT cells) vs. Ba/F3 cells expressing JAK2 V617F mutant (VF cells)

Project description:Transcriptional profiling of transformed Ba/F3 cells by myeloproliferative neoplasm-associated JAK2 V617F mutant comparing control Ba/F3 cells expressing wild type JAK2.

2013-10-31 | GSE34239 | GEO

RNA-seq Identification of Candidate Genes Differentially Expressed in DRN-BA(Pyr) and DRN-BA(PV) Neurons

Project description:To investigate the diversity of BA-projecting DRN(5-HT) neurons, we performed RNA-seq of BA(Pyr)- and BA(PV)-projecting DRN(5-HT) neurons and compared their gene expression levels.

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BA-Sulfate vs Cystine

Project description:Study of sulfur metabolism in BA

2010-11-25 | GSE25419 | GEO

Proteomic characterization of probiotics

Project description:The manufacturing processes of commercial probiotic strains may be affected in different ways in the attempt to optimize yield, costs, functionality, or stability, influencing gene expression, protein patterns, or metabolic output. Aim of this work was to compare different samples of a high concentration (450 billion bacteria) multispecies (8 strains) formulation produced at two different manufacturing sites, USA (US) and Italy (IT), by applying functional proteomics analyses. Several protein-profile differences were detected between IT- and US-made products, with Lactobacillus paracasei, Streptococcus thermophilus, and Bifidobacteria being the main affected probiotics/microorganisms. Integration of omics platforms with in vivo analysis emerged as a powerful tool to assess manufacturing procedures.

2020-01-22 | PXD017086 | Pride

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