High density foci in IDH1-mutated diffuse low-grade gliomas in adults

ABSTRACT: 20% of patients affected with diffuse low-grade brain tumors have high cell density foci harboring higher KI67 index and DNA alterations. These foci may represent tumor progression towards high-grade gliomas. Here we performed transcriptome analysis of those foci vs adjacent tumoral tissues dissected from formalin fixed and paraffin embedded blocks.

ORGANISM(S): Homo sapiens

PROVIDER: GSE130149 | GEO | 2020/03/17

REPOSITORIES: GEO