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Endoderm differentiation of human embryonic stem cells (hESCs) [RNA-Seq]

ABSTRACT: Purpose: The goal of this study is to identify the whole-genome transcriptome profiling of differentially expressed genes during human embryonic stem cell differentiation. Methods: Triplicate RNA profiles were generated from hESCs and induced endoderm cells, by deep sequencing with Illumina NextSeq 500. Results: We identified 6320 genes differentially expressed between hESCs and induced endoderm cells, with foldchange  1.5 and P < 0.05. Conclusion: Our study confirms that endodermal gene were dramatically induced during endoderm differentiation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE130340 | GEO | 2021/02/23

REPOSITORIES: GEO

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| PRJNA535525 | ENA