Transcriptomics

Dataset Information

Investigation of ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines


ABSTRACT: We identified that upregulation of ST8SIA1 promotes melanoma brain metastasis. The goal of this RNA-seq is to analyze the ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines (DP-0574 and WP-0614 cell lines) In vitro functional studies demonstrate that ST8SIA1 overexpression promotes cell proliferation and colony formation and that this can be halted by icaritin treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE130956 | GEO | 2024/04/30

REPOSITORIES: GEO

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