Induction of alpha cell-restricted Gc in dedifferentiating beta cells contributes to stress-induced beta-cell dysfunction [ChIP-seq]

ABSTRACT: To identify effector genes of pancreatic beta cell dedifferentiation and dysfunction, we integrated analyses of histone methylation as a surrogate of gene activation status and RNA expression in beta cells sorted from mice with multiparity-induced diabetes.

ORGANISM(S): Mus musculus

PROVIDER: GSE130996 | GEO | 2019/05/30

REPOSITORIES: GEO