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Induction of alpha cell-restricted Gc in dedifferentiating beta cells contributes to stress-induced beta-cell dysfunction [RNA-seq]

ABSTRACT: To identify effector genes of pancreatic beta cell dedifferentiation and dysfunction, we performed RNA expression in beta cells sorted from mice with multiparity-induced diabetes.

ORGANISM(S): Mus musculus

PROVIDER: GSE130997 | GEO | 2019/05/30

REPOSITORIES: GEO

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Induction of alpha cell-restricted Gc in dedifferentiating beta cells contributes to stress-induced beta-cell dysfunction [ChIP-seq]

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The Polycomb-dependent epigenome controls β-cell dysfunction, dedifferentiation and diabetes

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