Project description:The molecular mechanism underlying cardiac remodeling following exercise have been incompletely understood. Until now, most studies have been performed in rodents. We studied cardiac remodeling in the physiologically more relevant animal model, the swine. Microarray analysis was performed on animals that underwent either and exercise protocol or remained sedentary. RNA was isolated from tissue samples from the endocardial layer of the free wall of the left ventricle. RNA was isolated from 8 exercise-trained and 8 sedentary animals 4-5 weeks after start of the protocol. Each group contained 4 males and 4 females. Animals used for the study were 2-3 months old Yorkshire x Landrace swine. Only neutered males entered the study.

2014-06-01 | E-GEOD-37922 | biostudies-arrayexpress

Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.

Project description: Not available

| S-EPMC4670583 | biostudies-literature

Vitamin D receptor gene polymorphism predicts left ventricular hypertrophy in maintenance hemodialysis.

Project description: Not available

| S-EPMC8761333 | biostudies-literature

Oxytocin Protects Against Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting PI3K/AKT Pathway via a lncRNA GAS5/miR-375-3p/KLF4-Dependent Mechanism.

Project description: Not available

| S-EPMC8678504 | biostudies-literature

Left ventricular hypertrophy after hypertensive pregnancy disorders.

Project description: Not available