Next Generation Sequencing Analysis of Prenatal Chlorpyrifos Exposure embryonic kidneys

ABSTRACT: Purpose: In order to study signaling pathway changes of prenatal chlorpyrifos exposure embryonic kidney development Methods: By using RNA-seq, we studied the transcriptome of E12.5, E14.5, E16.5 and E18.5 prenatal chlorpyrifos exposure embryonic kidneys and DMSO exposure (control) embryonic kidneys Results: We show that Notch signaling pathway and aquaporin family had high expression in chlorpyrifos exposure E18.5 kidney. The nephron progenitor markers had low expression in chlorpyrifos exposure embryonic kidneys

ORGANISM(S): Mus musculus

PROVIDER: GSE131263 | GEO | 2019/06/30

REPOSITORIES: GEO