Basal and IL-4 response in DAP12 (TYROBP) KO mice

ABSTRACT: DAP12 is a transmembrane protein, expressed as a disulfide-bonded homodimer and bears an immunoreceptor tyrosine-based activation motif (ITAM). DAP12 is broadly expressed in hematopoietic cells and associates with a variety of cell surface receptors in lymphoid and myeloid cells. Macrophages express several DAP12-associated receptors including triggering receptors expressed by myeloid cells (TREM)-1,2 and 3, myeloid DAP12-associating lectin (MDL)-1, CD200R like proteins CD200R3/R4 and CD300C/D/E . Keywords: Cell type comparison

ORGANISM(S): Mus musculus

PROVIDER: GSE13140 | GEO | 2008/10/10

SECONDARY ACCESSION(S): PRJNA109571

REPOSITORIES: GEO