Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Dynlrb1 is Essential for Dynein Mediated Transport and Neuronal Survival

ABSTRACT: We identified Dynlrb1 as an essential gene for sensory neuron survival and performed RNA sequencing to identify the molecular mechanism mediating the role of Dynlrb1 in sensory neuron survival.

ORGANISM(S): Mus musculus

PROVIDER: GSE131455 | GEO | 2020/03/04

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Dynlrb1 is Essential for Dynein Mediated Transport and Neuronal Survival

Project description:Dynlrb1 is Essential for Dynein Mediated Transport and Neuronal Survival

| PRJNA543760 | ENA

DYNLRB1 is essential for dynein mediated transport and neuronal survival.

Project description: Not available

| S-EPMC7273200 | biostudies-literature

The General Transcription Factor TAF7 is Essential for Embryonic Development but Not Essential for the Survival or Differentiation of Mature T Cells

Project description:This SuperSeries is composed of the following subset Series: GSE34793: The General Transcription Factor TAF7 is Essential for Embryonic Development but Not Essential for the Survival or Differentiation of Mature T Cells (MEF data) GSE34795: The General Transcription Factor TAF7 is Essential for Embryonic Development but Not Essential for the Survival or Differentiation of Mature T Cells (T cell data) Refer to individual Series

2012-03-31 | E-GEOD-34796 | biostudies-arrayexpress

Developmental nicotine mediated gene expression and epigenetic change effects on neuronal structure and behavior [gene expression]

2016-05-30 | GSE80787 | GEO

Developmental nicotine mediated gene expression and epigenetic change effects on neuronal structure and behavior [gene expression]

Project description:Developmental nicotine exposure causes persistent changes in cortical neuron morphology and in behavior. We used microarray screening to identify master transcriptional or epigenetic regulators mediating these effects of nicotine mRNA prepared from dissected cortical tissue from mice that were administered saccharin or nicotine from conception through weaning at postnatal day 21 (pre- & postnatal period), and that were then allowed to remain nicotine-free until 3 months of age

2016-05-30 | E-GEOD-80787 | biostudies-arrayexpress

Post-transcriptionally regulated genes are essential for pluripotent stem cell survival

Project description:Post-transcriptionally regulated genes are essential for pluripotent stem cell survival

| PRJNA765014 | ENA

Post-transcriptionally regulated genes are essential for pluripotent stem cell survival

Project description:Post-transcriptionally regulated genes are essential for pluripotent stem cell survival

| PRJNA821543 | ENA

Neuronal cell lines as model dorsal root ganglion neurons: a transcriptomic comparison

Project description:Aim: Dorsal root ganglion neuron-derived immortal cell lines including ND7/23 and F-11 cells have been used extensively as in vitro model systems of native peripheral sensory neurons. However, while it is clear that some sensory neuron-specific receptors and ion channels are present in these cell lines, a systematic comparison of the molecular targets expressed by these cell lines with intact peripheral neurons is lacking. Methods: we examined the expression of RNA transcripts in the human neuroblastoma-derived cell line, SH-SY5Y, and two dorsal root ganglion hybridoma cell lines, F-11 and ND7/23, using Illumina next-generation sequencing. Results: The expression profile of these three cell lines did not resemble any specific dorsal root ganglion neuron subclass. The cell lines lacked many markers for nociceptive sensory neurons, such as the transient receptor potential V1 gene, but expressed markers for both myelinated and unmyelinated neurons. Conclusion: This paper provides insights into the receptor repertoire expressed in common dorsal root ganglion neuron-derived cell lines, and illustrates the limits and potentials of these cell lines as tools for neuropharmacological exploration.

2016-05-01 | GSE75811 | GEO

Myh9 plays essential role in hematopoietic stem/progenitor cells survival and maintenance

Project description:Myh9 plays essential role in hematopoietic stem/progenitor cells survival and maintenance

| PRJNA813848 | ENA

Project description:ABI induce sensory neuron

| PRJNA597624 | ENA