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16

Estrogen Regulates the JNK1 Genomic Localization Program in Breast Cancer Cells to Control Gene Expression and Cell Growth


ABSTRACT: JNK1 ChIP-chip and ER-alpha ChIP-chip were performed on NimbleGen genomic tiling arrays to understand the genomic binding patterns of this MAP kinase and receptor and their relationship to gene expression. Overall design: ChIP-chip analysis of JNK1 occupancy at promoters before and after estrogen treatment. 2 biological replicates (rep1 and rep2, rep3A and rep3B), 2 technical replicates each. ChIP-chip analysis of ER-alpha occupancy at promoters before and after estrogen treatment. 2 biological replicates, 2 technical replicates for one of the replicates (1 and 2).

INSTRUMENT(S): Homo sapiens 389K Hg18 RefSeq promoter

ORGANISM(S): Homo sapiens  

SUBMITTER: W. Lee Kraus   

PROVIDER: GSE13200 | GEO | 2012-04-01

SECONDARY ACCESSION(S): PRJNA109499

REPOSITORIES: GEO

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