Analysis of Roquin targetome during HCMV infection

ABSTRACT: To investigate how Roquin regulates cellular transcripts during Human cytomegalovirus (HCMV) infection, we examined the levels of cellular transcripts in cells treated control or Roquin-targeting siRNA during HCMV replication. Also, we performed Roquin crosslinking and immunoprecipitation followed by high-throughput sequencing (Roquin CLIP-seq) in HCMV-infected cells to identify which transcripts are directly bound by Roquin.

ORGANISM(S): Homo sapiens

PROVIDER: GSE132081 | GEO | 2019/08/15

REPOSITORIES: GEO