Genomic instability induced by chronic exposure of furfural in yeast

ABSTRACT: Furfural is a potential mutagenic agent. To explore the global effect of furfural on genomic intergrity, chromosomal alterations in 14 furfural-treated isolates of JSC25-1 strain were determined by whole genome SNP microarrays at a resolution about 1kb. Our results showed furfural exposure results in striking elevations of both mitotic recombination and aneuploidy events in yeast.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE132128 | GEO | 2019/06/04

REPOSITORIES: GEO