Validation of small molecule activators and identification of altered signaling pathways underlying the age-related decline in proliferative capacity in human dermal progenitors

ABSTRACT: Intrinsic dysfunction of hair follicle dermal progenitors underlies phenotypic changes observed in aged dermis in rodents. The authors confirm similar age-related decline in function is present in adult human DPCs. RNA-Seq is utilized to identify further explanations for this functional decline in aged hDPCs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE132383 | GEO | 2020/06/06

REPOSITORIES: GEO