Transcriptomics

Dataset Information

20

Expressionprofiling of a glnR-mutant of Mycobacterium tuberculosis during culture on nitrate


ABSTRACT: Identification of glnR-dependent regulation of nitrate assimilation Keywords: genetic modification Overall design: Mycobacterium tuberculosis H37Rv wild type and glnR mutant strain were incubated in minimal medium supplemented with 5 mM NO3 for 18 and 48 hours. RNA was extracted at indicated time points and microarray analysis was performed. Experiments were repeated once. As we wanted to focus on genes that were regulated steadily over time, data obtained from time points 18 hours and 48 hours were grouped. Thus for wild type and mutant, four independent data sets were obtained each, and compared using t-test statistics.

INSTRUMENT(S): HCI Mycobacterium tuberculosis H37Rv 5.5K [MTbH37Rva520456F]

ORGANISM(S): Mycobacterium tuberculosis H37Rv  

SUBMITTER: Robert Geffers   

PROVIDER: GSE13246 | GEO |

SECONDARY ACCESSION(S): PRJNA109525

REPOSITORIES: GEO

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