JAK2 inhibition in Philadelphia chromosome like acute lymphoblastic leukemia

ABSTRACT: CRLF2 rearranged Ph-like ALL cells are driven by oncogenic cytokine receptor signaling mediated by CRLF2 and JAK2. MHH-cALL4 cells were treated with ruxolotinib (JAK2 inhibitor) to provide insight into mechanisms of drug resistance.

ORGANISM(S): Homo sapiens

PROVIDER: GSE132486 | GEO | 2020/05/28

REPOSITORIES: GEO