Chromatin profiling of the relationship between EWS/FLI, LSD1, and the enhancer landscape - H3K4 methylation

ABSTRACT: The purpose of this study was to define the genome-wide functional relationship between LSD1 and EWS/FLI in Ewing sarcoma cells. We found EWS/FLI and LSD1 co-localize throughout the genome and that EWS/FLI induces a large change in the chromatin occupancy of LSD1.

ORGANISM(S): Homo sapiens

PROVIDER: GSE132709 | GEO | 2020/05/12

REPOSITORIES: GEO