Comparison of RhoE and RhoEα regulated pathways

ABSTRACT: We identified a new RhoE isoform, RhoEα, and compared the differentially regulated signalings by these two proteins. Both RhoE and RhoEα were first knocked out via CRISPR/Cas9 in HEK 293 cells and HeLa cells (KO cells), followed by RhoE and RhoEα reintroduction (RhoE reintroduction cells and RhoEα reintroduction cells, resepectively). Wild-type cells, KO cells, RhoE reintrocution cells, and RhoEα reintroduction cells were then subjected to RNA-seq analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE132718 | GEO | 2019/06/14

REPOSITORIES: GEO