Gene Expression data from the dentate gyrus of the defeated and control mice

ABSTRACT: Using various animal models, epigenetic mechanisms have been shown to be mediating the negative effects of chronic stressful events on the progression of depression and other neuropsychiatric disorders. However, non-coding RNAs, another layer of epigenetic regulation is relatively lesser studied in this context. We used mRNA microarrays to uncover dysregulation in miRNA-mRNA networks in the neurogenic dentate gyrus (DG) region of chronic social defeat stress (CSDS)-induced depressed mice by identifying tagets of the selected miRNAs from this list

ORGANISM(S): Mus musculus

PROVIDER: GSE132819 | GEO | 2019/07/17

REPOSITORIES: GEO