Genomics

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Streptococcus agalactiae genes controlled by the MtaR transcription factor


ABSTRACT: The purpose of this study was to determine what S. agalactiae genes are under the control of the MtaR regulatory protein. Inactivation of the Streptococcus agalactiae mtaR gene resulted in the downregulation of 11 genes and the upregulation of 1 gene in the mtaR mutant. Genes involved in the uptake of methionine and a gene involved in the degradation of peptides were downregulated. Also, genes involved in the transport and biosynthesis of arginine were downregulated. The gene encoding the virulence factor cspA was downregulated, as well as a gene showing similarity to plasminogen activators. Thus, the expression of genes involved in both metabolic functions and virulence are under the influence of mtaR.

ORGANISM(S): Streptococcus agalactiae

PROVIDER: GSE13325 | GEO | 2008/10/29

SECONDARY ACCESSION(S): PRJNA109919

REPOSITORIES: GEO

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